crf_metadata.csv

Title of CRF,Description,Study type,Version,Date of publication/release,Research questions,Target population,Inclusion Criteria,Exclusion Criteria,Pathogen or agent,Syndrome / clinical presentation,Setting,Geographic scope,Authors,Approvers,Institutions,Contact First Name,Contact Last Name,Contact email,Keywords,Relevant resources
ARChetype Disease CRF_Chikungunya,"A standardised ISARIC Case Report Form (CRF) for chikungunya, developed to harmonise clinical data collection in hospitalised patients during the acute phase of infection. It was produced through the ISARIC CRF development pipeline, using an existing dengue CRF as a template, variables extracted from expert-submitted study instruments and from the systematic review by Rama et al. (2024), and refined by international public consultation (15 experts across 11 countries). The CRF comprises a Presentation Form, a Daily Form, and an Outcome Form, and is available via ISARIC BRIDGE, which automatically generates a paper CRF, completion guide, and REDCap database file for deployment across diverse settings.",Observational,1,01/05/2026,"(1) characterise the clinical epidemiology of chikungunya, including presenting signs and symptoms, disease course, and outcomes;   (2) enable comparative clinical epidemiology across diseases, populations, and geographic regions;  (3) identify risk factors associated with disease presentation, progression, and outcomes;   (4) describe clinical management practices, including variations in approaches to care; (5) describe diagnostic approaches and results used in both routine clinical practice and research settings. ",Hospitalised adults during the acute phase of chikungunya infection.,Hospitalised individuals with suspected or laboratory-confirmed acute chikungunya virus infection.    ,Alternative confirmed diagnosis;,Chikungunya virus (CHIKV) - an alphavirus transmitted by Aedes aegypti and Aedes albopictus.,"Person who lives in or has traveled within the last 2 weeks to areas with chikungunya transmission and presents with fever associated with arthralgia or arthritis not explained by other medical conditions, with or without other extra-articular manifestations that may range from mild to severe.",Hospital,Global,"Anastasiia Demidova, Aileen Chang, Viviane S B de Oliveira, Josephine Bourner, Hugh Watson, Lubaba Sharin, Perkell Collie, Anastasia Kiseleva, Lilit Davtian, Jan Wu, Anastasiia Chernyavskaya, Sara Duque Vallejo, Esteban Garcia-Gallo, Dhruv Darji, Tom Edinburgh, Laura Merson, Daniel Munblit, and the Expert Working Group.","ISARIC chikungunya CRF management committee: Aileen Chang, Viviane S B de Oliveira, Josephine Bourner, Hugh Watson, Lubaba Sharin)","King's College London; ISARIC, Pandemic Sciences Institute, University of Oxford; George Washington University; Instituto Gonçalo Moniz (IGM), Fundação Oswaldo Cruz (Fiocruz) Bahia, and Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brazil; Antiviral Research Unit, Evotec ID, Lyon, France; Aarhus University, Denmark;  icddr,b (International Centre for Diarrhoeal Disease Research, Bangladesh), Dhaka, Bangladesh",Anastasiia,Demidova,anastasiia.demidova@kcl.ac.uk,chikungunya; CHIKV; arbovirus; case report form; CRF; ISARIC; BRIDGE; ARC; harmonised data collection; clinical characterisation; outbreak preparedness; REDCap; acute infection    ,ISARIC CRFs: https://isaric.org/resources/data/case-report-forms/   · BRIDGE: https://bridge.isaric.org/   · ARC variable library: https://github.com/ISARICResearch/ARC · ISARIC: www.isaric.org ·